Jawapan Tutorial DD Pulmonary

Type of Particle	Volume of water dispensed/used in each stages (ml)
	Inhaler	L-shape conducting portion	stage 1	stage 2	stage 3	stage 4	stage 5
A	100	100	20	20	20	20	20
B	100	100	20	20	20	20	20
Type of Particle	Concentration of model compounds (µg/ml)
	Inhaler	L-shape conducting portion	stage 1	stage 2	stage 3	stage 4	stage 5
A	20	55	15	12	10	8	4.5
B	25	75	22	18.5	17	14.5	6.5

total mass
cumulative mass
cumulative fraction

1. re-arrange the table by adding the cut-off size column
Particle A		da = 3.85
L-portion Throat
	cut-off size		Total mass		cumulative mass		cum.fraction
Stage 5	<1.7		90		90		9.1
Stage 4	1.7		160		250		25.3
Stage 3	3.1		200		450		45.5
Stage 2	6.8		240		690		69.7
Stage 1	13		300		990		100.0

normally ignore but get the value after extrapolation

MMAD = 3.8  GSD = 3.8/2.2 = 1.7

2. Plot particle cut-off size (x-axis) Vs cum. Fraction (Y-axis) on log-probability paper

Particle B	da= 3.79
L-portion Throat
	cut-off size	Total mass	cumulative mass	cum.fraction
Stage 5	<1.7	130	130	8.3
Stage 4	1.7	290	420	26.8
Stage 3	3.1	340	760	48.4
Stage 2	6.8	370	1130	72.0
Stage 1	13	440	1570	100.0

MMAD =	3.2
GSD =	3.2/1.7 = 1.8